| J Occup Health | year | 2004 | volume | 46 | number | 1 | page | 20 | - | 25 |
| Classification | Review | |||||||||
| Title | Application of DNA Microarrays in Occupational Health Research | |||||||||
| Author | Shinji KOIZUMI | |||||||||
| Organization | Department of Hazard Assessment, National Institute of Industrial Health, Japan | |||||||||
| Keywords | DNA microarray, occupational health, gene expression profiling | |||||||||
| Correspondence | S. Koizumi, Department of Hazard Assessment, National Institute of Industrial Health, 21-1, Nagao 6-chome, Tama-ku, Kawasaki 214-8585, Japan (e-mail: koizumi@niih.go.jp) | |||||||||
| Abstract | Application of DNA Microarrays in Occupational Health Research: Shinji KOIZUMI. Department of Hazard Assessment, National Institute of Industrial Health-The profiling of gene expression patterns with DNA microarrays is recently being widely used not only in basic molecular biological studies but also in the practical fields. In clinical application, for example, this technique is expected to be quite useful in making a correct diagnosis. In the pharmacological area, the microarray analysis can be applied to drug discovery and individualized drug treatment. Although not so popular as these examples, DNA microarrays could also be a powerful tool in studies relevant to occupational health. This review will describe the outline of gene expression profiling with DNA microarrays and prospects in occupational health research. | |||||||||